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The Emerging Roles and Therapeutic Potential of Soluble TREM2 in Alzheimer’s Disease
Alzheimer’s disease (AD) is the most common form of dementia characterized by the deposition of extracellular amyloid-β (Aβ)-containing plaques, the formation of intraneuronal neurofibrillary tangles as well as neuroinflammatory changes. As the key player in the brain innate immune system, microglia...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988790/ https://www.ncbi.nlm.nih.gov/pubmed/32038221 http://dx.doi.org/10.3389/fnagi.2019.00328 |