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The Emerging Roles and Therapeutic Potential of Soluble TREM2 in Alzheimer’s Disease

Alzheimer’s disease (AD) is the most common form of dementia characterized by the deposition of extracellular amyloid-β (Aβ)-containing plaques, the formation of intraneuronal neurofibrillary tangles as well as neuroinflammatory changes. As the key player in the brain innate immune system, microglia...

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Detalles Bibliográficos
Autores principales: Zhong, Li, Chen, Xiao-Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988790/
https://www.ncbi.nlm.nih.gov/pubmed/32038221
http://dx.doi.org/10.3389/fnagi.2019.00328