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Normalization Methods for the Analysis of Unbalanced Transcriptome Data: A Review

Dozens of normalization methods for correcting experimental variation and bias in high-throughput expression data have been developed during the last two decades. Up to 23 methods among them consider the skewness of expression data between sample states, which are even more than the conventional met...

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Detalles Bibliográficos
Autores principales: Liu, Xueyan, Li, Nan, Liu, Sheng, Wang, Jun, Zhang, Ning, Zheng, Xubin, Leung, Kwong-Sak, Cheng, Lixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988798/
https://www.ncbi.nlm.nih.gov/pubmed/32039167
http://dx.doi.org/10.3389/fbioe.2019.00358