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Normalization Methods for the Analysis of Unbalanced Transcriptome Data: A Review
Dozens of normalization methods for correcting experimental variation and bias in high-throughput expression data have been developed during the last two decades. Up to 23 methods among them consider the skewness of expression data between sample states, which are even more than the conventional met...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988798/ https://www.ncbi.nlm.nih.gov/pubmed/32039167 http://dx.doi.org/10.3389/fbioe.2019.00358 |