Prompting Fab Yeast Surface Display Efficiency by ER Retention and Molecular Chaperon Co-expression

For antibody discovery and engineering, yeast surface display (YSD) of antigen-binding fragments (Fabs) and coupled fluorescence activated cell sorting (FACS) provide intact paratopic conformations and quantitative analysis at the monoclonal level, and thus holding great promises for numerous applic...

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Detalles Bibliográficos
Autores principales: Mei, Meng, Li, Junhong, Wang, Shengchen, Lee, Ki Baek, Iverson, Brent L., Zhang, Guimin, Ge, Xin, Yi, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988814/
https://www.ncbi.nlm.nih.gov/pubmed/32039168
http://dx.doi.org/10.3389/fbioe.2019.00362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988814/
https://www.ncbi.nlm.nih.gov/pubmed/32039168
http://dx.doi.org/10.3389/fbioe.2019.00362

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