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Prompting Fab Yeast Surface Display Efficiency by ER Retention and Molecular Chaperon Co-expression
For antibody discovery and engineering, yeast surface display (YSD) of antigen-binding fragments (Fabs) and coupled fluorescence activated cell sorting (FACS) provide intact paratopic conformations and quantitative analysis at the monoclonal level, and thus holding great promises for numerous applic...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988814/ https://www.ncbi.nlm.nih.gov/pubmed/32039168 http://dx.doi.org/10.3389/fbioe.2019.00362 |