Metabolic syndrome diminishes insulin-induced Akt activation and causes a redistribution of Akt-interacting proteins in cardiomyocytes

Metabolic syndrome (MetS) is a cluster of cardiometabolic risk factors, with insulin resistance as a critical component for its development. Insulin signaling in the heart leads to Akt (also known as PKB) activation, a serine/threonine protein kinase, which regulates cardiac glucose metabolism and g...

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Detalles Bibliográficos
Autores principales: Landa-Galvan, Huguet V., Rios-Castro, Emmanuel, Romero-Garcia, Tatiana, Rueda, Angelica, Olivares-Reyes, Jesus Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988918/
https://www.ncbi.nlm.nih.gov/pubmed/31995605
http://dx.doi.org/10.1371/journal.pone.0228115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988918/
https://www.ncbi.nlm.nih.gov/pubmed/31995605
http://dx.doi.org/10.1371/journal.pone.0228115

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