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Ginger Extract Promotes Telomere Shortening and Cellular Senescence in A549 Lung Cancer Cells

[Image: see text] Replicative senescence, which is caused by telomere shortening from the end replication problem, is considered one of the tumor-suppressor mechanisms in eukaryotes. However, most cancers escape this replicative senescence by reactivating telomerase, an enzyme that extends the 3′-en...

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Detalles Bibliográficos
Autores principales: Kaewtunjai, Navakoon, Wongpoomchai, Rawiwan, Imsumran, Arisa, Pompimon, Wilart, Athipornchai, Anan, Suksamrarn, Apichart, Lee, T. Randall, Tuntiwechapikul, Wirote
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988994/
https://www.ncbi.nlm.nih.gov/pubmed/32010796
http://dx.doi.org/10.1021/acsomega.8b02853