Cargando…

A Novel Legionella Genomic Island Encodes a Copper-Responsive Regulatory System and a Single Icm/Dot Effector Protein Transcriptionally Activated by Copper

The intracellular pathogen Legionella pneumophila utilizes the Icm/Dot type IV secretion system to translocate >300 effector proteins into host cells during infection. The regulation of some of these effector-encoding genes was previously shown to be coordinated by several global regulators, incl...

Descripción completa

Detalles Bibliográficos
Autores principales: Linsky, Marika, Vitkin, Yevgeniya, Segal, Gil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989116/
https://www.ncbi.nlm.nih.gov/pubmed/31992628
http://dx.doi.org/10.1128/mBio.03232-19