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YAP regulates cell size and growth dynamics via non-cell autonomous mediators

The Hippo pathway regulates organ size, regeneration, and cell growth by controlling the stability of the transcription factor, YAP (Yorkie in Drosophila). When there is tissue damage, YAP is activated allowing the restoration of homeostatic tissue size. The exact signals by which YAP is activated a...

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Detalles Bibliográficos
Autores principales: Mugahid, Douaa, Kalocsay, Marian, Liu, Xili, Gruver, Jonathan Scott, Peshkin, Leonid, Kirschner, Marc W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989120/
https://www.ncbi.nlm.nih.gov/pubmed/31913124
http://dx.doi.org/10.7554/eLife.53404