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YAP regulates cell size and growth dynamics via non-cell autonomous mediators
The Hippo pathway regulates organ size, regeneration, and cell growth by controlling the stability of the transcription factor, YAP (Yorkie in Drosophila). When there is tissue damage, YAP is activated allowing the restoration of homeostatic tissue size. The exact signals by which YAP is activated a...
Autores principales: | Mugahid, Douaa, Kalocsay, Marian, Liu, Xili, Gruver, Jonathan Scott, Peshkin, Leonid, Kirschner, Marc W |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989120/ https://www.ncbi.nlm.nih.gov/pubmed/31913124 http://dx.doi.org/10.7554/eLife.53404 |
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