Intratumoral delivery of CCL25 enhances immunotherapy against triple-negative breast cancer by recruiting CCR9(+) T cells

CCR9(+) T cells have an increased potential to be activated and therefore may mediate strong antitumor responses. Here, we found, however, that CCL25, the only chemokine for CCR9(+) cells, is not expressed in human or murine triple-negative breast cancers (TNBCs), raising a hypothesis that intratumo...

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Detalles Bibliográficos
Autores principales: Chen, Hongmei, Cong, Xiuxiu, Wu, Chenxi, Wu, Xuan, Wang, Jialiang, Mao, Kuirong, Li, Jie, Zhu, Ge, Liu, Feiqi, Meng, Xiandi, Song, Jia, Sun, Xu, Wang, Xin, Liu, Shuhan, Zhang, Shi, Yang, Xianzhu, Song, Yanqiu, Yang, Yong-Guang, Sun, Tianmeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989134/
https://www.ncbi.nlm.nih.gov/pubmed/32064335
http://dx.doi.org/10.1126/sciadv.aax4690

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989134/
https://www.ncbi.nlm.nih.gov/pubmed/32064335
http://dx.doi.org/10.1126/sciadv.aax4690

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