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Extracellular matrix anisotropy is determined by TFAP2C-dependent regulation of cell collisions
The isotropic or anisotropic organisation of biological extracellular matrices has important consequences for tissue function. We study emergent anisotropy using fibroblasts that generate varying degrees of matrix alignment from uniform starting conditions. This reveals that the early migratory path...
Autores principales: | Park, Danielle, Wershof, Esther, Boeing, Stefan, Labernadie, Anna, Jenkins, Robert P, George, Samantha, Trepat, Xavier, Bates, Paul A, Sahai, Erik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989216/ https://www.ncbi.nlm.nih.gov/pubmed/31659294 http://dx.doi.org/10.1038/s41563-019-0504-3 |
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