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Population pharmacokinetic analysis of metformin administered as fixed-dose combination in Korean healthy adults
Metformin, an oral antihyperglycemic agent, is widely used as the first-line pharmacotherapy for type 2 diabetes mellitus (T2DM). It has been in use for several decades as numerous different formulations. However, despite its use, population pharmacokinetic (PK) modeling of metformin is not well dev...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Clinical Pharmacology and Therapeutics
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989222/ https://www.ncbi.nlm.nih.gov/pubmed/32055544 http://dx.doi.org/10.12793/tcp.2018.26.1.25 |