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Population pharmacokinetic analysis of metformin administered as fixed-dose combination in Korean healthy adults

Metformin, an oral antihyperglycemic agent, is widely used as the first-line pharmacotherapy for type 2 diabetes mellitus (T2DM). It has been in use for several decades as numerous different formulations. However, despite its use, population pharmacokinetic (PK) modeling of metformin is not well dev...

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Detalles Bibliográficos
Autores principales: Choi, Suein, Jeon, Sangil, Han, Seunghoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Clinical Pharmacology and Therapeutics 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989222/
https://www.ncbi.nlm.nih.gov/pubmed/32055544
http://dx.doi.org/10.12793/tcp.2018.26.1.25