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Comparison of various estimation methods for the parameters of Michaelis-Menten equation based on in vitro elimination kinetic simulation data
The Michaelis-Menten equation is one of the best-known models describing the enzyme kinetics of in vitro drug elimination experiments, and takes a form of equation relating reaction rate (V) to the substrate concentration ([S]) via the maximum reaction rate (V(max)) and the Michaelis constant (K(m))...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Korean Society for Clinical Pharmacology and Therapeutics
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989224/ https://www.ncbi.nlm.nih.gov/pubmed/32055546 http://dx.doi.org/10.12793/tcp.2018.26.1.39 |