Development of a physiologically-based pharmacokinetic model for cyclosporine in Asian children with renal impairment

This study aimed to assess the pharmacokinetics of cyclosporine A (CsA) in Asian children with renal impairment (RI) by developing a physiologically-based pharmacokinetic (PBPK) model with Simcyp Simulator. The PBPK model of Asian children with RI was developed by modifying the physiological paramet...

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Detalles Bibliográficos
Autores principales: Yoon, Sumin, Yi, Sojeong, Rhee, Su-jin, Lee, Hyun A, Kim, Yun, Yu, Kyung-Sang, Chung, Jae-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Clinical Pharmacology and Therapeutics 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989237/
https://www.ncbi.nlm.nih.gov/pubmed/32055591
http://dx.doi.org/10.12793/tcp.2019.27.3.107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989237/
https://www.ncbi.nlm.nih.gov/pubmed/32055591
http://dx.doi.org/10.12793/tcp.2019.27.3.107

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