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Pharmacodynamic principles and target concentration intervention

This tutorial reviews the principles of dose individualisation with an emphasis on target concentration intervention (TCI). Once a target effect is chosen then pharmacodynamics can predict the target concentration and pharmacokinetics can predict the target dose to achieve the required response. Dos...

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Detalles Bibliográficos
Autor principal: Holford, Nick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Clinical Pharmacology and Therapeutics 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989251/
https://www.ncbi.nlm.nih.gov/pubmed/32055568
http://dx.doi.org/10.12793/tcp.2018.26.4.150