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Effect of plasma membrane monoamine transporter genetic variants on pharmacokinetics of metformin in humans
Metformin, an oral hypoglycemic agent belonging to biguanide class, is widely used to treat type 2 diabetes mellitus, and several drug transporters such as organic cation transporters (OCTs), multidrug and toxin extrusion transporter (MATE), and plasma membrane monoamine transporter (PMAT) are thoug...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Clinical Pharmacology and Therapeutics
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989255/ https://www.ncbi.nlm.nih.gov/pubmed/32055553 http://dx.doi.org/10.12793/tcp.2018.26.2.79 |