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Effect of plasma membrane monoamine transporter genetic variants on pharmacokinetics of metformin in humans

Metformin, an oral hypoglycemic agent belonging to biguanide class, is widely used to treat type 2 diabetes mellitus, and several drug transporters such as organic cation transporters (OCTs), multidrug and toxin extrusion transporter (MATE), and plasma membrane monoamine transporter (PMAT) are thoug...

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Detalles Bibliográficos
Autores principales: Moon, Seol Ju, Oh, Jaeseong, Lee, Seung Hwan, Choi, Yewon, Yu, Kyung-Sang, Chung, Jae-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Clinical Pharmacology and Therapeutics 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989255/
https://www.ncbi.nlm.nih.gov/pubmed/32055553
http://dx.doi.org/10.12793/tcp.2018.26.2.79