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Characterization of circadian blood pressure patterns using non-linear mixed effects modeling

Characterizing the time course of baseline or pre-drug blood pressure is important in acquiring unbiased estimates of antihypertensive drug effect. In this study, we recruited 23 healthy male volunteers and measured systolic (SBP) and diastolic blood pressure (DBP) over 24 hours on an hourly basis....

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Detalles Bibliográficos
Autores principales: Chae, Dongwoo, Kim, Yukyung, Park, Kyungsoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Clinical Pharmacology and Therapeutics 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989266/
https://www.ncbi.nlm.nih.gov/pubmed/32055578
http://dx.doi.org/10.12793/tcp.2019.27.1.24