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Quantification of apixaban in human plasma using ultra performance liquid chromatography coupled with tandem mass spectrometry

Apixaban, an inhibitor of direct factor Xa, is used for the treatment of venous thromboembolic events or prevention of stroke. Unlike many other anticoagulant agents, it does not need periodic monitoring. However, monitoring is still required to determine the risk of bleeding due to overdose or surg...

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Detalles Bibliográficos
Autores principales: Jeong, Hyeon-Cheol, Kim, Tae-Eun, Shin, Kwang-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Clinical Pharmacology and Therapeutics 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989270/
https://www.ncbi.nlm.nih.gov/pubmed/32055579
http://dx.doi.org/10.12793/tcp.2019.27.1.33