Allelic H3K27me3 to allelic DNA methylation switch maintains noncanonical imprinting in extraembryonic cells

Faithful maintenance of genomic imprinting is essential for mammalian development. While germline DNA methylation–dependent (canonical) imprinting is relatively stable during development, the recently found oocyte-derived H3K27me3-mediated noncanonical imprinting is mostly transient in early embryos...

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Detalles Bibliográficos
Autores principales: Chen, Zhiyuan, Yin, Qiangzong, Inoue, Azusa, Zhang, Chunxia, Zhang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989337/
https://www.ncbi.nlm.nih.gov/pubmed/32064321
http://dx.doi.org/10.1126/sciadv.aay7246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989337/
https://www.ncbi.nlm.nih.gov/pubmed/32064321
http://dx.doi.org/10.1126/sciadv.aay7246

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