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HUNK phosphorylates EGFR to regulate breast cancer metastasis

Epidermal growth factor receptor (EGFR) is commonly over-expressed in metastatic breast cancer yet metastatic breast cancer is generally resistant to anti-EGFR therapies, and the mechanism for resistance to EGFR inhibitors in this setting is not fully understood. Hormonally up-regulated neu-associat...

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Detalles Bibliográficos
Autores principales: Williams, Carly B., Phelps-Polirer, Kendall, Dingle, Ivan P., Williams, Christina J., Rhett, Matthew J., Eblen, Scott T., Armeson, Kent, Hill, Elizabeth G., Yeh, Elizabeth S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989402/
https://www.ncbi.nlm.nih.gov/pubmed/31597954
http://dx.doi.org/10.1038/s41388-019-1046-5