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MicroRNA-17-92 Regulates Beta-Cell Restoration After Streptozotocin Treatment

Objective: To clarify the role and mechanism of miR-17-92 cluster in islet beta-cell repair after streptozotocin intervention. Methods: Genetically engineered mice (miR-17-92βKO) and control RIP-Cre mice were intraperitoneally injected with multiple low dose streptozotocin. Body weight, random blood...

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Detalles Bibliográficos
Autores principales: Wan, Shan, Zhang, Jie, Chen, Xiang, Lang, Jiangli, Li, Li, Chen, Fei, Tian, Li, Meng, Yang, Yu, Xijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989481/
https://www.ncbi.nlm.nih.gov/pubmed/32038500
http://dx.doi.org/10.3389/fendo.2020.00009