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Tissue pO(2) distributions in xenograft tumors dynamically imaged by Cherenkov-excited phosphorescence during fractionated radiation therapy
Hypoxia in solid tumors is thought to be an important factor in resistance to therapy, but the extreme microscopic heterogeneity of the partial pressures of oxygen (pO(2)) between the capillaries makes it difficult to characterize the scope of this phenomenon without invasive sampling of oxygen dist...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989492/ https://www.ncbi.nlm.nih.gov/pubmed/31996677 http://dx.doi.org/10.1038/s41467-020-14415-9 |