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Tissue pO(2) distributions in xenograft tumors dynamically imaged by Cherenkov-excited phosphorescence during fractionated radiation therapy

Hypoxia in solid tumors is thought to be an important factor in resistance to therapy, but the extreme microscopic heterogeneity of the partial pressures of oxygen (pO(2)) between the capillaries makes it difficult to characterize the scope of this phenomenon without invasive sampling of oxygen dist...

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Detalles Bibliográficos
Autores principales: Cao, Xu, Rao Allu, Srinivasa, Jiang, Shudong, Jia, Mengyu, Gunn, Jason R., Yao, Cuiping, LaRochelle, Ethan P., Shell, Jennifer R., Bruza, Petr, Gladstone, David J., Jarvis, Lesley A., Tian, Jie, Vinogradov, Sergei A., Pogue, Brian W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989492/
https://www.ncbi.nlm.nih.gov/pubmed/31996677
http://dx.doi.org/10.1038/s41467-020-14415-9