A Novel Loss-of-Function Variant in the Chloride Ion Channel Gene Clcn2 Associates with Atrial Fibrillation

Atrial Fibrillation (AF) is the most common cardiac arrhythmia. Its pathogenesis is complex and poorly understood. Whole exome sequencing of Danish families with AF revealed a novel four nucleotide deletion c.1041_1044del in CLCN2 shared by affected individuals. We aimed to investigate the role of g...

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Detalles Bibliográficos
Autores principales: Hansen, Thea Hyttel, Yan, Yannan, Ahlberg, Gustav, Vad, Oliver Bundgaard, Refsgaard, Lena, dos Santos, Joana Larupa, Mutsaers, Nancy, Svendsen, Jesper Hastrup, Olesen, Morten Salling, Bentzen, Bo Hjorth, Schmitt, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989500/
https://www.ncbi.nlm.nih.gov/pubmed/31996765
http://dx.doi.org/10.1038/s41598-020-58475-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989500/
https://www.ncbi.nlm.nih.gov/pubmed/31996765
http://dx.doi.org/10.1038/s41598-020-58475-9

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