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Unbalance Between Sarcoplasmic Reticulum Ca(2 +) Uptake and Release: A First Step Toward Ca(2 +) Triggered Arrhythmias and Cardiac Damage
The present review focusses on the regulation and interplay of cardiac SR Ca(2+) handling proteins involved in SR Ca(2+) uptake and release, i.e., SERCa2/PLN and RyR2. Both RyR2 and SERCA2a/PLN are highly regulated by post-translational modifications and/or different partners’ proteins. These contro...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989610/ https://www.ncbi.nlm.nih.gov/pubmed/32038301 http://dx.doi.org/10.3389/fphys.2019.01630 |