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Unbalance Between Sarcoplasmic Reticulum Ca(2 +) Uptake and Release: A First Step Toward Ca(2 +) Triggered Arrhythmias and Cardiac Damage

The present review focusses on the regulation and interplay of cardiac SR Ca(2+) handling proteins involved in SR Ca(2+) uptake and release, i.e., SERCa2/PLN and RyR2. Both RyR2 and SERCA2a/PLN are highly regulated by post-translational modifications and/or different partners’ proteins. These contro...

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Detalles Bibliográficos
Autores principales:	Federico, Marilén, Valverde, Carlos A., Mattiazzi, Alicia, Palomeque, Julieta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989610/ https://www.ncbi.nlm.nih.gov/pubmed/32038301 http://dx.doi.org/10.3389/fphys.2019.01630

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