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A Hyaluronan-binding Peptide (P15-1) Reduces Inflammatory and Catabolic Events in IL-1β-treated Human Articular Chondrocytes

Inflammation plays a critical role in osteoarthritis (OA). It stimulates catabolic events in articular chondrocytes and prevents chondrogenic precursor cells from repairing cartilage lesions, leading to accelerated cartilage degradation. Therefore, the identification of novel factors that reduce cat...

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Detalles Bibliográficos
Autores principales: Shortt, Claire, Luyt, Leonard G., Turley, Eva A., Cowman, Mary K., Kirsch, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989647/
https://www.ncbi.nlm.nih.gov/pubmed/31996703
http://dx.doi.org/10.1038/s41598-020-57586-7