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A Hyaluronan-binding Peptide (P15-1) Reduces Inflammatory and Catabolic Events in IL-1β-treated Human Articular Chondrocytes
Inflammation plays a critical role in osteoarthritis (OA). It stimulates catabolic events in articular chondrocytes and prevents chondrogenic precursor cells from repairing cartilage lesions, leading to accelerated cartilage degradation. Therefore, the identification of novel factors that reduce cat...
Autores principales: | Shortt, Claire, Luyt, Leonard G., Turley, Eva A., Cowman, Mary K., Kirsch, Thorsten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989647/ https://www.ncbi.nlm.nih.gov/pubmed/31996703 http://dx.doi.org/10.1038/s41598-020-57586-7 |
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