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Preparation of single- and double-oligonucleotide antibody conjugates and their application for protein analytics

Oligonucleotide-conjugated antibodies have gained importance for their use in protein diagnostics. The possibility to transfer the readout signal from the protein to the DNA level with an oligonucleotide-conjugated antibody increased the sensitivity of protein assays by orders of magnitude and enabl...

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Detalles Bibliográficos
Autores principales: Wiener, Julius, Kokotek, Daniel, Rosowski, Simon, Lickert, Heiko, Meier, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989672/
https://www.ncbi.nlm.nih.gov/pubmed/31996713
http://dx.doi.org/10.1038/s41598-020-58238-6