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Positive surface charge of GluN1 N-terminus mediates the direct interaction with EphB2 and NMDAR mobility
Localization of the N-methyl-D-aspartate type glutamate receptor (NMDAR) to dendritic spines is essential for excitatory synaptic transmission and plasticity. Rather than remaining trapped at synaptic sites, NMDA receptors undergo constant cycling into and out of the postsynaptic density. Receptor m...
Autores principales: | Washburn, Halley R., Xia, Nan L., Zhou, Wei, Mao, Yu-Ting, Dalva, Matthew B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989673/ https://www.ncbi.nlm.nih.gov/pubmed/31996679 http://dx.doi.org/10.1038/s41467-020-14345-6 |
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