Differential Repair Protein Recruitment at Sites of Clustered and Isolated DNA Double-Strand Breaks Produced by High-Energy Heavy Ions

DNA double-strand break (DSB) repair is crucial to maintain genomic stability. The fidelity of the repair depends on the complexity of the lesion, with clustered DSBs being more difficult to repair than isolated breaks. Using live cell imaging of heavy ion tracks produced at a high-energy particle a...

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Detalles Bibliográficos
Autores principales: Jakob, Burkhard, Dubiak-Szepietowska, Monika, Janiel, Ellen, Schmidt, Alina, Durante, Marco, Taucher-Scholz, Gisela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989695/
https://www.ncbi.nlm.nih.gov/pubmed/31996740
http://dx.doi.org/10.1038/s41598-020-58084-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989695/
https://www.ncbi.nlm.nih.gov/pubmed/31996740
http://dx.doi.org/10.1038/s41598-020-58084-6

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