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Actinomyces Produces Defensin-Like Bacteriocins (Actifensins) with a Highly Degenerate Structure and Broad Antimicrobial Activity

We identified a strain of Actinomyces ruminicola which produces a potent bacteriocin with activity against a broad range of Gram-positive bacteria, many of which are pathogenic to animals and humans. The bacteriocin was purified and found to have a mass of 4,091 ± 1 Da with a sequence of GFGCNLITSNP...

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Detalles Bibliográficos
Autores principales: Sugrue, Ivan, O’Connor, Paula M., Hill, Colin, Stanton, Catherine, Ross, R. Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989792/
https://www.ncbi.nlm.nih.gov/pubmed/31767775
http://dx.doi.org/10.1128/JB.00529-19