The effect of two selective A(1)‐receptor agonists and the bitopic ligand VCP746 on heart rate and regional vascular conductance in conscious rats

BACKGROUND AND PURPOSE: Adenosine is a local mediator that regulates physiological and pathological processes via activation of four GPCRs (A(1), A(2A), A(2B), and A(3)). We have investigated the effect of two A(1)‐receptor‐selective agonists and the novel A(1)‐receptor bitopic ligand VCP746 on the...

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Detalles Bibliográficos
Autores principales: Cooper, Samantha L., March, Julie, Sabbatini, Andrea R., Hill, Stephen J., Jörg, Manuela, Scammells, Peter J., Woolard, Jeanette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989947/
https://www.ncbi.nlm.nih.gov/pubmed/31596949
http://dx.doi.org/10.1111/bph.14870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989947/
https://www.ncbi.nlm.nih.gov/pubmed/31596949
http://dx.doi.org/10.1111/bph.14870

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