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The effect of two selective A(1)‐receptor agonists and the bitopic ligand VCP746 on heart rate and regional vascular conductance in conscious rats
BACKGROUND AND PURPOSE: Adenosine is a local mediator that regulates physiological and pathological processes via activation of four GPCRs (A(1), A(2A), A(2B), and A(3)). We have investigated the effect of two A(1)‐receptor‐selective agonists and the novel A(1)‐receptor bitopic ligand VCP746 on the...
Autores principales: | Cooper, Samantha L., March, Julie, Sabbatini, Andrea R., Hill, Stephen J., Jörg, Manuela, Scammells, Peter J., Woolard, Jeanette |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989947/ https://www.ncbi.nlm.nih.gov/pubmed/31596949 http://dx.doi.org/10.1111/bph.14870 |
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