Paratope Duality and Gullying are Among the Atypical Recognition Mechanisms Used by a Trio of Nanobodies to Differentiate Ebolavirus Nucleoproteins

We had previously shown that three anti–Marburg virus nanobodies (VHH or single-domain antibody [sdAb]) targeted a cryptotope within an alpha-helical assembly at the nucleoprotein (NP) C-terminus that was conserved through half a century of viral evolution. Here, we wished to determine whether an an...

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Detalles Bibliográficos
Autores principales: Sherwood, Laura Jo, Taylor, Alexander Bryan, Hart, Peter John, Hayhurst, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990103/
https://www.ncbi.nlm.nih.gov/pubmed/31626803
http://dx.doi.org/10.1016/j.jmb.2019.10.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990103/
https://www.ncbi.nlm.nih.gov/pubmed/31626803
http://dx.doi.org/10.1016/j.jmb.2019.10.005

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