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Transmissible Gastroenteritis Virus Infection Up-Regulates FcRn Expression via Nucleocapsid Protein and Secretion of TGF-β in Porcine Intestinal Epithelial Cells

Transmissible gastroenteritis virus (TGEV) is a porcine intestinal coronavirus that causes fatal severe watery diarrhea in piglets. The neonatal Fc receptor (FcRn) is the only IgG transport receptor, its expression on mucosal surfaces is triggered upon viral stimulation, which significantly enhances...

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Detalles Bibliográficos
Autores principales: Qian, Shaoju, Gao, Zitong, Cao, Rui, Yang, Kang, Cui, Yijie, Li, Shaowen, Meng, Xianrong, He, Qigai, Li, Zili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990134/
https://www.ncbi.nlm.nih.gov/pubmed/32038538
http://dx.doi.org/10.3389/fmicb.2019.03085