Cargando…

Transmissible Gastroenteritis Virus Infection Up-Regulates FcRn Expression via Nucleocapsid Protein and Secretion of TGF-β in Porcine Intestinal Epithelial Cells

Transmissible gastroenteritis virus (TGEV) is a porcine intestinal coronavirus that causes fatal severe watery diarrhea in piglets. The neonatal Fc receptor (FcRn) is the only IgG transport receptor, its expression on mucosal surfaces is triggered upon viral stimulation, which significantly enhances...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qian, Shaoju, Gao, Zitong, Cao, Rui, Yang, Kang, Cui, Yijie, Li, Shaowen, Meng, Xianrong, He, Qigai, Li, Zili
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990134/ https://www.ncbi.nlm.nih.gov/pubmed/32038538 http://dx.doi.org/10.3389/fmicb.2019.03085

Ejemplares similares

TGEV infection up-regulates FcRn expression via activation of NF-κB signaling
por: Guo, Jinyue, et al.
Publicado: (2016)

Characterization of the Rabbit Neonatal Fc Receptor (FcRn) and Analyzing the Immunophenotype of the Transgenic Rabbits That Overexpresses FcRn
por: Catunda Lemos, Ana Paula, et al.
Publicado: (2012)

The Role of FcRn in Antigen Presentation
por: Baker, Kristi, et al.
Publicado: (2014)

The Neonatal Fc Receptor (FcRn): A Misnomer?
por: Pyzik, Michal, et al.
Publicado: (2019)

The neonatal Fc receptor in cancer FcRn in cancer
por: Cadena Castaneda, Diana, et al.
Publicado: (2020)

Roles of FcRn in Antigen-Presenting Cells during Autoimmunity and a Clinical Evaluation of Efgartigimod as an FcRn Blocker
por: Zhou, Yihan, et al.
Publicado: (2023)

FcRn is mother’s milk to allergen tolerance
por: Lambrecht, Bart N.
Publicado: (2018)

In Translation: FcRn across the Therapeutic Spectrum
por: Qi, Timothy, et al.
Publicado: (2021)

Megalin Orchestrates FcRn Endocytosis and Trafficking
por: Dahlke, Eileen, et al.
Publicado: (2022)

Selection of bispecific antibodies with optimal developability using FcRn‑Ph‑HPLC as an optimized FcRn affinity chromatography method
por: Müller, Thomas, et al.
Publicado: (2023)

FcRN receptor antagonists in the management of myasthenia gravis
por: Bhandari, Vinaya, et al.
Publicado: (2023)

FcRn Overexpression Expands Diversity of the Humoral Immune Response in bFcRn Transgenic Mice
por: Szikora, Bence, et al.
Publicado: (2020)

The importance of FcRn in neuro-immunotherapies: From IgG catabolism, FCGRT gene polymorphisms, IVIg dosing and efficiency to specific FcRn inhibitors
por: Dalakas, Marinos C., et al.
Publicado: (2021)

Pharmacokinetic Models for FcRn-Mediated IgG Disposition
por: Xiao, Jim J.
Publicado: (2012)

Cell surface dynamics and cellular distribution of endogenous FcRn
por: D’Hooghe, Lena, et al.
Publicado: (2017)

Targeting FcRn for immunomodulation: Benefits, risks, and practical considerations
por: Peter, Hans-Hartmut, et al.
Publicado: (2020)

Human IgE does not bind to human FcRn
por: Brinkhaus, Maximilian, et al.
Publicado: (2022)

FcRn Expression in Wildtype Mice, Transgenic Mice, and in Human Tissues
por: Li, Tommy, et al.
Publicado: (2018)

FcRn inhibitors: a novel option for the treatment of myasthenia gravis
por: Zhu, Li-Na, et al.
Publicado: (2023)

FcRn receptor-mediated pharmacokinetics of therapeutic IgG in the eye
por: Kim, Hyuncheol, et al.
Publicado: (2009)

Abundant Intracellular IgG in Enterocytes and Endoderm Lacking FcRn
por: Mohanty, Sudhasri, et al.
Publicado: (2013)

Response to “The Role of FcRn in the Pharmacokinetics of Biologics in Patients with Multiple Myeloma”
por: Xu, Xu Steven, et al.
Publicado: (2017)

Human FcRn Tissue Expression Profile and Half-Life in PBMCs
por: Fan, Yao-Yun, et al.
Publicado: (2019)

An FcRn-targeted mucosal vaccine against SARS-CoV-2 infection and transmission
por: Li, Weizhong, et al.
Publicado: (2022)

An FcRn-targeted mucosal vaccine against SARS-CoV-2 infection and transmission
por: Li, Weizhong, et al.
Publicado: (2023)

The Fab region of IgG impairs the internalization pathway of FcRn upon Fc engagement
por: Brinkhaus, Maximilian, et al.
Publicado: (2022)

Harnessing Fc/FcRn Affinity Data from Patents with Different Machine Learning Methods
por: Dumet, Christophe, et al.
Publicado: (2023)

FcRn mediated IgG transport by retinal pigment epithelium cells
por: Korthagen, Nicoline M, et al.
Publicado: (2012)

Charge-mediated influence of the antibody variable domain on FcRn-dependent pharmacokinetics
por: Schoch, Angela, et al.
Publicado: (2015)

Algorithmic multiscale analysis for the FcRn mediated regulation of antibody PK in human
por: Patsatzis, Dimitris G., et al.
Publicado: (2022)

FcRn as a Transporter for Nasal Delivery of Biologics: A Systematic Review
por: Fieux, Maxime, et al.
Publicado: (2021)

Human FcRn Is a Two-in-One Attachment-Uncoating Receptor for Echovirus 18
por: Chen, Xiangpeng, et al.
Publicado: (2022)

Characterization of the interactions of rabbit neonatal Fc receptor (FcRn) with rabbit and human IgG isotypes
por: Szikora, Bence, et al.
Publicado: (2017)

Human and Non-Human Primate Intestinal FcRn Expression and Immunoglobulin G Transcytosis
por: Hornby, Pamela J., et al.
Publicado: (2013)

Interactions of IgG1 CH2 and CH3 Domains with FcRn
por: Ying, Tianlei, et al.
Publicado: (2014)

Unraveling the Interaction between FcRn and Albumin: Opportunities for Design of Albumin-Based Therapeutics
por: Sand, Kine Marita Knudsen, et al.
Publicado: (2015)

Factors Affecting the FcRn-Mediated Transplacental Transfer of Antibodies and Implications for Vaccination in Pregnancy
por: Wilcox, Christopher R., et al.
Publicado: (2017)

Lack of FcRn Impairs Natural Killer Cell Development and Functions in the Tumor Microenvironment
por: Castaneda, Diana Cadena, et al.
Publicado: (2018)

Monoclonal Antibody Engineering and Design to Modulate FcRn Activities: A Comprehensive Review
por: Ramdani, Yanis, et al.
Publicado: (2022)

The endosomal system of primary human vascular endothelial cells and albumin–FcRn trafficking
por: Pannek, Andreas, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_ba73pg3mp1a2jbq2rjpbdcg8bd