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CD163(ΔSRCR5) MARC-145 Cells Resist PRRSV-2 Infection via Inhibiting Virus Uncoating, Which Requires the Interaction of CD163 With Calpain 1

Porcine alveolar macrophages without the CD163 SRCR5 domain are resistant to porcine reproductive and respiratory syndrome virus (PRRSV) infection. However, whether the deletion of CD163 SRCR5 in MARC-145 cells confers resistance to PRRSV and interaction of which of the host proteins with CD163 is i...

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Detalles Bibliográficos
Autores principales: Yu, Piao, Wei, Ruiping, Dong, Wenjuan, Zhu, Zhenbang, Zhang, Xiaoxiao, Chen, Yaosheng, Liu, Xiaohong, Guo, Chunhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990145/
https://www.ncbi.nlm.nih.gov/pubmed/32038556
http://dx.doi.org/10.3389/fmicb.2019.03115