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Multiscale Modeling of Dyadic Structure-Function Relation in Ventricular Cardiac Myocytes

Cardiovascular disease is often related to defects of subcellular components in cardiac myocytes, specifically in the dyadic cleft, which include changes in cleft geometry and channel placement. Modeling of these pathological changes requires both spatially resolved cleft as well as whole cell level...

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Detalles Bibliográficos
Autores principales: Cosi, Filippo G., Giese, Wolfgang, Neubert, Wilhelm, Luther, Stefan, Chamakuri, Nagaiah, Parlitz, Ulrich, Falcke, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990380/
https://www.ncbi.nlm.nih.gov/pubmed/31635789
http://dx.doi.org/10.1016/j.bpj.2019.09.023