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Mesenchymal stem cells derived from iPSCs expressing interleukin-24 inhibit the growth of melanoma in the tumor-bearing mouse model

BACKGROUND: Interleukin-24 (IL-24) is a therapeutic gene for melanoma, which can induce melanoma cell apoptosis. Mesenchymal stem cells (MSCs) show promise as a carrier to delivery anti-cancer factors to tumor tissues. Induced pluripotent stem cells (iPSCs) are an alternative source of mesenchymal s...

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Detalles Bibliográficos
Autores principales: Wu, Zheng, Liu, Wei, Wang, Zujia, Zeng, Baitao, Peng, Guangnan, Niu, Hongyan, Chen, Linlin, Liu, Cong, Hu, Qian, Zhang, Yuxuan, Pan, Mengmeng, Wu, Lingqian, Liu, Mujun, Liu, Xionghao, Liang, Desheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990536/
https://www.ncbi.nlm.nih.gov/pubmed/32015693
http://dx.doi.org/10.1186/s12935-020-1112-7