The effects of common structural variants on 3D chromatin structure

BACKGROUND: Three-dimensional spatial organization of chromosomes is defined by highly self-interacting regions 0.1–1 Mb in size termed Topological Associating Domains (TADs). Genetic factors that explain dynamic variation in TAD structure are not understood. We hypothesize that common structural va...

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Detalles Bibliográficos
Autores principales: Shanta, Omar, Noor, Amina, Sebat, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990566/
https://www.ncbi.nlm.nih.gov/pubmed/32000688
http://dx.doi.org/10.1186/s12864-020-6516-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990566/
https://www.ncbi.nlm.nih.gov/pubmed/32000688
http://dx.doi.org/10.1186/s12864-020-6516-1

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