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The effects of common structural variants on 3D chromatin structure
BACKGROUND: Three-dimensional spatial organization of chromosomes is defined by highly self-interacting regions 0.1–1 Mb in size termed Topological Associating Domains (TADs). Genetic factors that explain dynamic variation in TAD structure are not understood. We hypothesize that common structural va...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990566/ https://www.ncbi.nlm.nih.gov/pubmed/32000688 http://dx.doi.org/10.1186/s12864-020-6516-1 |