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Acid and inflammatory sensitisation of naked mole-rat colonic afferent nerves

Acid sensing in the gastrointestinal tract is required for gut homeostasis and the detection of tissue acidosis caused by ischaemia, inflammation and infection. In the colorectum, activation of colonic afferents by low pH contributes to visceral hypersensitivity and abdominal pain in human disease i...

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Detalles Bibliográficos
Autores principales: Hockley, James RF, Barker, Katie H, Taylor, Toni S, Callejo, Gerard, Husson, Zoe M, Bulmer, David C, Smith, Ewan St. J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990608/
https://www.ncbi.nlm.nih.gov/pubmed/31992138
http://dx.doi.org/10.1177/1744806920903150