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Synthesis and Formulation of Four-Arm PolyDMAEA-siRNA Polyplex for Transient Downregulation of Collagen Type III Gene Expression in TGF-β1 Stimulated Tenocyte Culture

[Image: see text] The natural healing process for tendon repair is associated with high upregulation of collagen type III, leading to scar tissue and tendon adhesions with functionally deficient tendons. Gene delivery systems are widely reported as potential nanotherapeutics to treat diseases, provi...

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Detalles Bibliográficos
Autores principales: Liao, Xin, Falcon, Noelia D, Mohammed, Ali A, Paterson, Yasmin Z., Mayes, Andrew Geoffrey, Guest, Deborah J., Saeed, Aram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990625/
https://www.ncbi.nlm.nih.gov/pubmed/32010823
http://dx.doi.org/10.1021/acsomega.9b03216