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Synthesis and Formulation of Four-Arm PolyDMAEA-siRNA Polyplex for Transient Downregulation of Collagen Type III Gene Expression in TGF-β1 Stimulated Tenocyte Culture
[Image: see text] The natural healing process for tendon repair is associated with high upregulation of collagen type III, leading to scar tissue and tendon adhesions with functionally deficient tendons. Gene delivery systems are widely reported as potential nanotherapeutics to treat diseases, provi...
Autores principales: | Liao, Xin, Falcon, Noelia D, Mohammed, Ali A, Paterson, Yasmin Z., Mayes, Andrew Geoffrey, Guest, Deborah J., Saeed, Aram |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990625/ https://www.ncbi.nlm.nih.gov/pubmed/32010823 http://dx.doi.org/10.1021/acsomega.9b03216 |
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