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Impaired Glucocorticoid Receptor Dimerization Aggravates LPS-Induced Circulatory and Pulmonary Dysfunction

Background: Sepsis, that can be modeled by LPS injections, as an acute systemic inflammation syndrome is the most common cause for acute lung injury (ALI). ALI induces acute respiratory failure leading to hypoxemia, which is often associated with multiple organ failure (MOF). During systemic inflamm...

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Detalles Bibliográficos
Autores principales: Wepler, Martin, Preuss, Jonathan M., Merz, Tamara, Hartmann, Clair, Wachter, Ulrich, McCook, Oscar, Vogt, Josef, Kress, Sandra, Gröger, Michael, Fink, Marina, Scheuerle, Angelika, Möller, Peter, Calzia, Enrico, Burret, Ute, Radermacher, Peter, Tuckermann, Jan P., Vettorazzi, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990631/
https://www.ncbi.nlm.nih.gov/pubmed/32038649
http://dx.doi.org/10.3389/fimmu.2019.03152