Oral delivery of novel human IGF-1 bioencapsulated in lettuce cells promotes musculoskeletal cell proliferation, differentiation and diabetic fracture healing

Human insulin-like growth factor-1 (IGF-1) plays important roles in development and regeneration of skeletal muscles and bones but requires daily injections or surgical implantation. Current clinical IGF-1 lacks e-peptide and is glycosylated, reducing functional efficacy. In this study, codon-optimi...

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Detalles Bibliográficos
Autores principales: Park, J., Yan, G., Kwon, K.-C., Liu, M., Gonnella, P.A., Yang, S., Daniell, H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990632/
https://www.ncbi.nlm.nih.gov/pubmed/31870566
http://dx.doi.org/10.1016/j.biomaterials.2019.119591

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990632/
https://www.ncbi.nlm.nih.gov/pubmed/31870566
http://dx.doi.org/10.1016/j.biomaterials.2019.119591

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