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Evaluation of Plasma Microbial Cell-Free DNA Sequencing to Predict Bloodstream Infection in Pediatric Patients With Relapsed or Refractory Cancer

IMPORTANCE: Bloodstream infection (BSI) is a common, life-threatening complication of treatment for cancer. Predicting BSI before onset of clinical symptoms would enable preemptive therapy, but there is no reliable screening test. OBJECTIVE: To estimate sensitivity and specificity of plasma microbia...

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Detalles Bibliográficos
Autores principales: Goggin, Kathryn P., Gonzalez-Pena, Veronica, Inaba, Yuki, Allison, Kim J., Hong, David K., Ahmed, Asim A., Hollemon, Desiree, Natarajan, Sivaraman, Mahmud, Ousman, Kuenzinger, William, Youssef, Sarah, Brenner, Abigail, Maron, Gabriela, Choi, John, Rubnitz, Jeffrey E., Sun, Yilun, Tang, Li, Wolf, Joshua, Gawad, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990667/
https://www.ncbi.nlm.nih.gov/pubmed/31855231
http://dx.doi.org/10.1001/jamaoncol.2019.4120