A Unified Continuous Flow Assembly Line Synthesis of Highly Substituted Pyrazoles and Pyrazolines

A rapid and modular continuous flow synthesis of highly functionalized fluorinated pyrazoles and pyrazolines has been developed. Flowing fluorinated amines through sequential reactor coils mediates diazoalkane formation and [3+2] cycloaddition to generate more than 30 azoles in a telescoped fashion....

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Detalles Bibliográficos
Autores principales: Britton, Joshua, Jamison, Timothy F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Blackwell 2017
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990874/
https://www.ncbi.nlm.nih.gov/pubmed/28544160
http://dx.doi.org/10.1002/anie.201704529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990874/
https://www.ncbi.nlm.nih.gov/pubmed/28544160
http://dx.doi.org/10.1002/anie.201704529

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