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Therapeutic Targeting of the Macrophage Immune Checkpoint CD47 in Myeloid Malignancies

In recent years, immunotherapies have been clinically investigated in AML and other myeloid malignancies. While most of these are focused on stimulating the adaptive immune system (including T cell checkpoint inhibitors), several key approaches targeting the innate immune system have been identified...

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Detalles Bibliográficos
Autores principales: Chao, Mark P., Takimoto, Chris H., Feng, Dong Dong, McKenna, Kelly, Gip, Phung, Liu, Jie, Volkmer, Jens-Peter, Weissman, Irving L., Majeti, Ravindra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990910/
https://www.ncbi.nlm.nih.gov/pubmed/32038992
http://dx.doi.org/10.3389/fonc.2019.01380